ARED Organism -- expansion of ARED reveals AU-rich element cluster variations between human and mouse

What you can do:
View AREs in the human transcriptome and study the comparative genomics of AREs in model organisms.
Highlights:
  • ARED Organism represents the expansion of the adenylate uridylate (AU)-rich element (ARE)-containing human mRNA database into the transcriptomes of mouse and rat.
  • Quantitative assessment of ARE conservation in human, mouse and rat transcripts was performed, indicating that a significant proportion (approximately 25%) of human genes differ in their ARE patterns from mouse and rat transcripts.
  • ARED-Integrated, another updated and expanded version of ARED, is a compilation of ARED versions 1.0 to 3.0 and updated version 4.0 that is devoted to human mRNAs.
Keywords:
  • AU-rich element-containing mRNA
  • AU-rich elements
  • adenylate uridylate-rich elements
  • AREs
  • ARE alternative forms
  • mRNA turnover
  • human Adenylate Uridylate Rich Elements
  • comparative genomics
  • human transcriptome
  • mouse transcriptome
  • rat transcriptome
This record last updated: 03-03-2008
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