SELEX_DB -- A database on in vitro selected oligomers adapted for recognizing natural sites and for analyzing both SNPs and site-directed mutagenesis data

URL:

http://wwwmgs.bionet.nsc.ru/mgs/systems/selex/

What you can do:

Search for information on both the experimental data on in vitro selected DNA/RNA oligomers (aptamers) and the applets for these oligomers recognition.

Highlights:

The in vitro selected aptamers are very informative for the Single Nucleotide Polymorphism (SNP) analysis.
the in vitro selected aptamers are very informative for the Single Nucleotide Polymorphism (SNP) analysis.
The latest release of the SELEX_DB has been supported by two databases SYSTEM and CROSS_TEST, storing both experiment systems and their cross-validation tests.
Implementation of the cross-validation tests demonstrates that in eukaryotes in vitro selected set of sites is more similar to the natural site set than to the other in vitro selected set of sequences of homologous or other related proteins.

Keywords:

aptamers
DNA oligomers
RNA oligomers
SNPs analysis
Single Nucleotide Polymorphism analysis
protein-binding sequences
DNA-binding sites

Literature & Tutorials:

PubMed Link: SELEX_DB

This record last updated: 05-09-2005

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