PSORTb v.2.0 -- expanded prediction of bacterial protein subcellular localization and insights gained from comparative proteome analysis.

What you can do:
Predict bacterial protein subcellular localizations.
  • PSORT-B examines a given protein sequence for amino acid composition, similarity to proteins of known localization, presence of a signal peptide, transmembrane alpha-helices and motifs corresponding to specific localizations.
  • A probabilistic method integrates these analyses, returning a list of five possible localization sites with associated probability scores.
  • The program attains a precision of 96% for Gram-positive and Gram-negative bacteria and predictive coverage comparable to other tools for whole proteome analysis.
  • The proportion of proteins at each localization is remarkably consistent across species, even in species with varying proteome size.
  • This dataset, the largest of its kind, is freely available, along with the PSORT-B source code
  • protein localizations
  • protein subcellular localizations
  • signal peptide prediction tool
  • protein localization prediction tool
  • protein subcellular localization prediction tool
  • bacterial protein subcellular localizations
  • bacterial protein localizations
  • Gram-negative bacteria
  • Gram-positive bacteria
  • signal peptide
  • transmembrane alpha-helices
  • localization signals
  • localization signal prediction
This record last updated: 06-15-2005
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