ELM -- Eukarotic Linear Motif Resource
URL:
What you can do:
Predict functional sites in eukaryotic proteins.
Highlights:
- The ELM resource provides an expanding knowledge base, currently covering 146 known motifs, with annotation that includes >1300 experimentally reported instances.
- It is also an exploratory tool for suggesting new candidates of known linear motifs in proteins of interest. I
- nformation about protein domains, protein structure and native disorder, cellular and taxonomic contexts is used to reduce or deprecate false positive matches.
- Results are graphically displayed in a 'Bar Code' format, which also displays known instances from homologous proteins through a novel 'Instance Mapper' protocol based on PHI-BLAST.
- ELM server output provides links to the ELM annotation as well as to a number of remote resources.
- Using the links, researchers can explore the motifs, proteins, complex structures and associated literature to evaluate whether candidate motifs might be worth experimental investigation.
Keywords:
- protein functional sites
- protein functional site prediction tool
- protein modification sites
- protein modification site prediction tool
- protein binding sites
- protein binding site prediction tool
- protein motif analysis tool
- eukaryotic proteins
- eukaryotic protein functional sites
Literature & Tutorials:
This record last updated: 01-25-2010