Analyze DNA sequences and compute the DNA helical stability.
Highlights:
WEB-THERMODYN analyzes DNA sequences and computes the free energy required to unwind and separate the strands of the double helix.
A helical stability profile across a selected DNA region or the entire sequence is generated by sliding-window analysis.
WEB-THERMODYN can predict sites of low helical stability present at regulatory regions for transcription and replication and can be used to test the influence of mutations.