GeneFizz -- a web tool to compare genetic (coding/non-coding) and physical (helix/coil) segmentations of DNA sequences. Gene discovery and evolutionary perspectives
Compare between genetic (coding/non-coding) and physics (helix/coil) segmentations of DNA sequences.
Highlights:
This web tool permits the direct comparison between two types of segmentations for DNA sequences (possibly annotated): the coding/non-coding segmentation associated with genomic annotations (simple genes or exons in split genes) and the physics-based structural segmentation between helix and coil domains (as provided by the classical helix-coil model).
GeneFizz can be used for two purposes: ab initio physics-based identification of new genes or the exploration of possible evolutionary signals revealed by the discrepancies observed between the two types of information.