DiANNA -- unified software for Cysteine state, Disulfide Bond partner prediction and ternary cysteine classification
What you can do:
Predict the disulfide bond topology and partner in a protein based on its sequence.
Highlights:
- DiANNA is a artificial neural network and web server, which determines the cysteine oxidation state and disulfide connectivity of a protein, given only its amino acid sequence.
- In version 1.1 of DiANNA (2006), its functionality was extended by applying a support vector machine with spectrum kernel for the cysteine classification problem-to determine whether a cysteine is reduced (free in sulfhydryl state), half-cystine (involved in a disulfide bond) or bound to a metallic ligand. In the latter case, DiANNA predicts the ligand among iron, zinc, cadmium and carbon.
Keywords:
- disulphides
- disulphide bonds
- disulfides
- disulfide bonds
- disulfide bonds prediction tool
- disulfide connectivity prediction tool
- Cysteine oxidation state prediction tool
- protein structure analysis tool
- protein sequence analysis tool
- ternary cysteine classification tool
Literature & Tutorials:
PubMed Link: DiANNA -- a web server for disulfide connectivity prediction
PubMed Link of 2006 update: DiANNA 1.1: an extension of the DiANNA web server for ternary cysteine classification
PubMed Link of 2006 update: DiANNA 1.1: an extension of the DiANNA web server for ternary cysteine classification
This record last updated: 7-20-2006