The HHpred interactive server for protein homology detection and structure prediction

What you can do:
Detect homology and predict structures among distantly related proteins.
Highlights:
  • HHpred is a fast server for remote protein homology detection and structure prediction and is the first to implement pairwise comparison of profile hidden Markov models (HMMs).
  • It allows to search a wide choice of databases, such as the PDB, SCOP, Pfam, SMART, COGs and CDD.
  • It accepts a single query sequence or a multiple alignment as input, and it returns the search results in a user-friendly format similar to that of PSI-BLAST.
  • Search options include local or global alignment and scoring secondary structure similarity.
  • HHpred can produce pairwise query-template alignments, multiple alignments of the query with a set of templates selected from the search results, as well as 3D structural models that are calculated by the MODELLER software from these alignments.
Keywords:
  • protein sequence alignment tool
  • protein structure alignment tool
  • multiple sequence alignment
  • protein homology detection
  • protein structure prediction tool
This record last updated: 01-05-2021
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