T-Reg Comparator -- an analysis tool for the comparison of position weight matrices
What you can do:
Compare a set of position weight matrices (PWM) against the T-Reg database,a relational database on transcriptional regulation that contains a collection of PWMs.
Highlights:
- T-Reg Comparator is a novel software tool designed to support research into transcriptional regulation. Sequence motifs representing transcription factor binding sites are usually encoded as position weight matrices.
- The user inputs a set of such weight matrices or binding site sequences and our program matches them against the T-Reg database, which is presently built on data from the Transfac.
- The tool delivers a detailed report on similarities between user-supplied motifs and motifs in the database.
- Apart from simple one-to-one relationships, T-Reg Comparator is also able to detect similarities between submatrices.
- In addition, the Web server provides a user interface to a program for sequence scanning with weight matrices.
- Typical areas of application for T-Reg Comparator are motif and regulatory module finding and annotation of regulatory genomic regions.
Keywords:
- transcription factor binding site prediction tool
- transcription factor binding site analysis tool
- DNA-binding sites prediction tool
- cis-elements prediction tool
- cis-regulatory elements prediction tool
- DNA sequence analysis tool
- promoter analysis tool
- promoter elements prediction tool
- transcription factors
- response elements
- cis-elements
- cis-regulatory modules analysis tool
- regulatory motifs
- regulatory motif discovery tool
Literature & Tutorials:
This record last updated: 11-21-2005