ChimerDB -- A Knowledgebase for fusion sequences
What you can do:
Search for fusion sequences in human, mouse and rat genomes.
Highlights:
- ChimerDB is a knowledgebase of fusion genes identified from bioinformatics analysis of transcript sequences in the GenBank and various other public resources such as the Sanger cancer genome project (CGP), OMIM, PubMed and the Mitelman's database.
- The new, updated algorithm is more sensitive and has detected 2699 fusion transcripts with high confidence.
- It can identify interchromosomal translocations as well as the intrachromosomal deletions or inversions of large DNA segments.
- Results from the analysis of next-generation sequencing data in the short read archives are incorporated as well.
- A new alignment viewer was developed that that should facilitate examining reliability of fusion transcripts and inferring functional significance.
Keywords:
- Chromosome translocation
- gene fusion
- fusion transcripts
- fusion transcript identification tool
- gene splicing
- Cytogenetic band data
- exon
- intron
- human gene fusion
- rat gene fusion
- mouse gene fusion
- gene fusion data
Literature & Tutorials:
PubMed Link: ChimerDB -- A Knowledgebase for fusion sequences
-- 2010 Update: ChimerDB 2.0--a knowledgebase for fusion genes updated
-- 2010 Update: ChimerDB 2.0--a knowledgebase for fusion genes updated
This record last updated: 01-12-2010