ABS -- a database of Annotated regulatory Binding Sites from orthologous promoters

What you can do:
Search for known binding sites in promoters of orthologous vertebrate genes.
Highlights:
  • ABS is a public database of known binding sites identified in promoters of orthologous vertebrate genes that have been manually curated from bibliography.
  • It contains 650 annotated experimental binding sites from 68 transcription factors and 100 orthologous target genes in human, mouse, rat or chicken genome sequences.
  • Computational predictions and promoter alignment information are also provided for each entry.
  • A simple and easy-to-use web interface facilitates data retrieval allowing different views of the information.
  • In addition, the 2006 release 1.0 of ABS includes a customizable generator of artificial datasets based on the known sites contained in the collection and an evaluation tool to aid during the training and the assessment of motif-finding programs.
  • ABS is aimed to become a standard collection of high-quality data is important to design, evaluate and improve novel computational approaches to identify binding motifs on promoter sequences from related genes.
Keywords:
  • transcription factor binding site analysis tool
  • DNA-binding sites prediction tool
  • promoter analysis tool
  • transcription starting site prediction tool
  • transcription factor binding sites
  • transcription factor binding site visualization tool
  • transcription factors
  • cis-elements
  • cis-elements prediction tool
  • regulatory element prediction tool
  • promoter element prediction tool
  • orthologous genes
  • orthologous gene promoter analysis tool
  • vertebrate genes
This record last updated: 01-13-2006
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