HTPSELEX x97 a database of high-throughput SELEX libraries for transcription factor binding sites
What you can do:
Search for transcription factor binding sites sequences obtained with SELEX and high-throughput SELEX method.
Highlights:
- HTPSELEX is a public database providing access to primary and derived data from high-throughput SELEX experiments aimed at characterizing the binding specificity of transcription factors.
- The resource is primarily intended to serve computational biologists interested in building models of transcription factor binding sites from large sets of binding sequences.
- For each experiment, we try to provide accurate information about the protein material used, details of the wet lab protocol, an archive of sequencing trace files, assembled clone sequences (concatemers) and complete sets of in vitro selected protein-binding tags. In addition, we offer in-house derived binding sites models.
- HTPSELEX also offers reasonably large SELEX libraries obtained with conventional low-throughput protocols.
- The FTP site (ftp://ftp.isrec.isb-sib.ch/pub/databases/htpselex/) contains the trace archives and database flatfiles.
- The web server offers user-friendly interfaces for viewing individual entries and quality-controlled download of SELEX sequence libraries according to a user-defined sequencing quality threshold.
Keywords:
- transcription factor binding sites
- DNA-binding sites
- transcription factor binding sites
- transcription factors
- transcription factor
- cis-elements
- regulatory elements
- promoter elements
- high-throughput SELEX
- CTF/NF1
- LEF/TCF
Literature & Tutorials:
This record last updated: 01-17-2006