VIPERdb -- Virus Particle Explorer Database
What you can do:
Search for information on icosahedral virus capsid structures.
Highlights:
- VIPERdb is a relational database and a web portal for icosahedral virus capsid structures.
- The database's aim is to provide a comprehensive resource specific to the needs of the virology community, with an emphasis on the description and comparison of derived data from structural and computational analyses of the virus capsids.
- In the current release, a novel method was implemented to represent capsid protein residues in the icosahedral asymmetric unit (IAU) using azimuthal polar orthographic projections, otherwise known as Phi-Psi (Phi-Psi) diagrams.
- In conjunction with a new Application Programming Interface (API), these diagrams can be used as a dynamic interface to the database to map residues (categorized as surface, interface and core residues) and identify family wide conserved residues including hotspots at the interfaces.
- The interactivity with the database was enhanced by interfacing with web-based tools.
- The applications Jmol and STRAP were implemented to visualize and interact with the virus molecular structures and provide sequence-structure alignment capabilities.
Keywords:
- macromolecular structure
- structural virology
- icosahedral virus capsid structures
- virus structure analysis
Literature & Tutorials:
This record last updated: 02-18-2009