VIPERdb -- Virus Particle Explorer Database

What you can do:
Search for information on icosahedral virus capsid structures.
Highlights:
  • VIPERdb is a relational database and a web portal for icosahedral virus capsid structures.
  • The database's aim is to provide a comprehensive resource specific to the needs of the virology community, with an emphasis on the description and comparison of derived data from structural and computational analyses of the virus capsids.
  • In the current release, a novel method was implemented to represent capsid protein residues in the icosahedral asymmetric unit (IAU) using azimuthal polar orthographic projections, otherwise known as Phi-Psi (Phi-Psi) diagrams.
  • In conjunction with a new Application Programming Interface (API), these diagrams can be used as a dynamic interface to the database to map residues (categorized as surface, interface and core residues) and identify family wide conserved residues including hotspots at the interfaces.
  • The interactivity with the database was enhanced by interfacing with web-based tools.
  • The applications Jmol and STRAP were implemented to visualize and interact with the virus molecular structures and provide sequence-structure alignment capabilities.
Keywords:
  • macromolecular structure
  • structural virology
  • icosahedral virus capsid structures
  • virus structure analysis
This record last updated: 02-18-2009
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