gpDB -- a database of G-proteins and their interaction with GPCRs

What you can do:
Search for information on G-proteins and their interactions with GPCRs.
Highlights:
  • gpDB is a publicly accessible, relational database, containing information about G-proteins, G-protein coupled receptors (GPCRs) and effectors, as well as information concerning known interactions between these molecules.
  • The sequences are classified according to a hierarchy of different classes, families and subfamilies based on literature search.
  • The main innovation besides the classification of G-proteins, GPCRs and effectors is the relational model of the database, describing the known coupling specificity of GPCRs to their respective alpha subunits of G-proteins, and also the specific interaction between G-proteins and their effectors.
Keywords:
  • G proteins
  • G protein information portal
  • G protein-coupled receptors
  • G protein coupling specificity
  • GPCRs
  • signal transduction
This record last updated: 01-11-2010
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