KEGG PATHWAY Database

What you can do:
Search a collection of pathway maps on metabolism, signal transduction, gene regulation, and cellular processes.
Highlights:
  • In the KEGG database resource, diseases are viewed as perturbed states of the molecular system, and drugs as perturbants to the molecular system.
  • Disease information is computerized in two forms: pathway maps and gene/molecule lists.
  • The KEGG PATHWAY database contains pathway maps for the molecular systems in both normal and perturbed states.
  • In the KEGG DISEASE database, each disease is represented by a list of known disease genes, any known environmental factors at the molecular level, diagnostic markers and therapeutic drugs, which may reflect the underlying molecular system.
  • The KEGG DRUG database contains chemical structures and/or chemical components of all drugs in Japan, including crude drugs and TCM (Traditional Chinese Medicine) formulas, and drugs in the USA and Europe.
  • This database also captures knowledge about two types of molecular networks: the interaction network with target molecules, metabolizing enzymes, other drugs, etc. and the chemical structure transformation network in the history of drug development.
  • The new disease/drug information resource named KEGG MEDICUS can be used as a reference knowledge base for computational analysis of molecular networks, especially, by integrating large-scale experimental datasets.
Keywords:
  • pathway map
  • metabolic pathway
  • biosynthetic pathway
  • signal transduction pathway
  • protein biosynthesis pathway
  • RNA protein biosynthesis pathway
  • cellular process pathway
  • human disease
  • drug development
  • Target Based Structure Classification
  • Skeleton Based Structure Classification
  • hormone signaling pathways
  • olfactory transduction
  • cell growth
  • cell death
  • apoptosis
  • receptors
  • ABC transporter
This record last updated: 02-11-2010
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