HARMONY -- a server for the assessment of protein structures

What you can do:
Examine the compatibility between the sequence and the three-dimensional structure of a protein.
Highlights:
  • HARMONY is a procedure that examines the compatibility between the sequence and the structure of a protein by assigning scores to individual residues and their amino acid exchange patterns after considering their local environments, such as the backbone conformation, solvent accessibility and hydrogen bonding patterns.
  • Users can submit their protein structure files and, if required, the alignment of homologous sequences.
  • Scores are mapped on the structure for subsequent examination that is useful to also recognize regions of possible local errors in protein structures.
Keywords:
  • protein structure analysis tool
  • protein structure validation tool
This record last updated: 07-24-2006
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