Predict protein binding sites in a protein sequence based on geometrical analysis of protein tertiary substructures.
Highlights:
Protemot web server carries out prediction of protein binding sites based on the structural templates automatically extracted from the crystal structures of protein-ligand complexes in the PDB (Protein Data Bank).
In its 2006 release, 1051 distinctive templates of protein binding sites have been identified from 5146 protein-ligand complex crystal structures.
Experimental results show that Protemot can deliver a superior prediction power than a web server based on a manually curated template library with insufficient quantity of entries.