VISTA Enhancer Browserx97a database of tissue-specific human enhancers
What you can do:
Search for information on experimentally validated human noncoding fragments with gene enhancer activity as assessed in transgenic mice.
Highlights:
- This growing database currently (as of Feb. 2007) contains over 301 experimentally tested DNA fragments, of which more than 115 have been validated as tissue-specific enhancers.
- For each positive enhancer, digital images of whole-mount embryo staining at embryonic day 11.5 and an anatomical description of the reporter gene expression pattern are provided.
- Users can retrieve elements near single genes of interest, search for enhancers that target reporter gene expression to a particular tissue, or download entire collections of enhancers with a defined tissue specificity or conservation depth.
Keywords:
- human gene enhancers
- human tissue-specific enhancers
- human cis-regulatory elements
- human gene expression regulation
- human gene expression patterns
- human gene regulatory elements
- human non-coding DNA elements
- human developmental enhancers
- comparative gene expression patterns
- human exonic splicing enhancers
- human gene splicing
- human exonic splicing enhancers
- human ESE
- gene splicing
- transgenic mice
Literature & Tutorials:
This record last updated: 02-27-2007