RegTransBase x97- a database of regulatory sequences and interactions in a wide range of prokaryotic genomes
What you can do:
Search for manually curated regulatory interactions in prokaryotes that captures the knowledge in public scientific literature using a controlled vocabulary.
Highlights:
- RegTransBase describes a large number of regulatory interactions reported in many organisms.
- It contains the following types of experimental data: the activation or repression of transcription by an identified direct regulator, determining the transcriptional regulatory function of a protein (or RNA) directly binding to DNA (RNA), mapping or prediction of a binding site for a regulatory protein and characterization of regulatory mutations.
- As of 2007, RegTransBase content is derived from about 3459 relevant articles describing over 8118 experiments in relation to 157 microbes.
- It contains data on the regulation of about 9579 genes and evidence for 7524 interactions with 790 regulators and 656 effectors.
- RegTransBase also contains manually created position weight matrices (PWM) that can be used to identify candidate regulatory sites in over 60 species.
Keywords:
- prokaryotic regulatory interactions
- bacterial transcription regulation
- prokaryotic transcription factors
- prokaryotic transcription factor binding sites prediction
- prokaryotic regulatory site position weight matrices
- bacterial regulatory elements
- bacterial DNA-binding sites
- bacterial promoter elements
- bacterial cis-regulatory elements
- regulatory proteins
- regulatory mutations
- microbial gene regulation
- regulators
- effectors
Literature & Tutorials:
This record last updated: 03-21-2007