PeroxisomeDB -- a database for the peroxisomal proteome, functional genomics and disease
What you can do:
Search for integrated genetic and functional information on peroxisomal genes in human and yeast.
Highlights:
- PeroxisomeDB organizes the peroxisomal proteome of humans and Saccharomyces cerevisiae based on genetic and functional information into metabolic categories with a special focus on peroxisomal disease.
- The new release adds peroxisomal proteins from 35 newly sequenced eukaryotic genomes including fungi, yeasts, plants and lower eukaryotes.
- It includes a core ensemble of 139 peroxisomal protein families and 2706 putative peroxisomal protein homologs.
- Approximately 37% of the identified homologs contained putative peroxisome targeting signals (PTS).
- The new database includes phylogenetic trees for 2386 of the peroxisomal proteins. Additional features include s a tool to capture kinetic information from Brenda, CheBI and Sabio-RK databases and more than 1400 selected bibliographic references.
Keywords:
- Peroxisomes
- human peroxisomal proteome
- Saccharomyces cerevisiae yeast proteome
- peroxisomal metabolic pathways
- peroxisomal proteins
- peroxisomal genes
- targeting signal (PTS) motifs
- lipid metabolism
- antioxidant metabolism
- genetic diseases
- organelle
- organellar proteome
Literature & Tutorials:
This record last updated: 03-22-2010