OligoCalc -- An online oligonucleotide properties calculator

What you can do:
Calculate DNA and RNA single-stranded and double-stranded properties, including molecular weight, solution concentration, melting temperature, estimated absorbance coefficients, inter-molecular self-complementarity estimation and intra-molecular hairpin loop formation.
Highlights:
  • OligoCalc provides a convenient web interface for calculating the physical properties of DNA and RNA oligonucleotides including melting temperature, molecular weight, %GC content and absorbance coefficient for a given oligonucleotide sequence.
  • OligoCalc has a familiar x91calculatorx92 look and feel, making it readily understandable and usable.
  • OligoCalc incorporates three common methods for calculating oligonucleotide-melting temperatures, including a nearest-neighbor thermodynamic model for melting temperature.
Keywords:
  • Algorithms
  • Base Composition
  • Computational Biology/*methods
  • DNA/*chemistry
  • Models, Chemical
  • Oligonucleotides/*chemistry/*genetics
  • RNA/*chemistry
  • Temperature
  • User-Computer Interface
This record last updated: 09-28-2007
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