OligoCalc -- An online oligonucleotide properties calculator
What you can do:
Calculate DNA and RNA single-stranded and double-stranded properties, including molecular weight, solution concentration, melting temperature, estimated absorbance coefficients, inter-molecular self-complementarity estimation and intra-molecular hairpin loop formation.
Highlights:
- OligoCalc provides a convenient web interface for calculating the physical properties of DNA and RNA oligonucleotides including melting temperature, molecular weight, %GC content and absorbance coefficient for a given oligonucleotide sequence.
- OligoCalc has a familiar x91calculatorx92 look and feel, making it readily understandable and usable.
- OligoCalc incorporates three common methods for calculating oligonucleotide-melting temperatures, including a nearest-neighbor thermodynamic model for melting temperature.
Keywords:
- Algorithms
- Base Composition
- Computational Biology/*methods
- DNA/*chemistry
- Models, Chemical
- Oligonucleotides/*chemistry/*genetics
- RNA/*chemistry
- Temperature
- User-Computer Interface
Literature & Tutorials:
This record last updated: 09-28-2007