Biodefense Proteomics Resource Center
What you can do:
Discover candidates for the next generation of vaccines, therapeutics and diagnostics against NIAID's Category A, B and C priority pathogens.
Highlights:
- The NIAID-funded Biodefense Proteomics Resource Center (RC) provides storage, dissemination, visualization and analysis capabilities for the experimental data deposited by seven Proteomics Research Centers (PRCs).
- The data includes transcriptional profiles, protein profiles, protein structural data and host-pathogen protein interactions, in the context of the pathogen life cycle in vivo and in vitro.
- The database has stored and supported host or pathogen data derived from Bacillus, Brucella, Cryptosporidium, Salmonella, SARS, Toxoplasma, Vibrio and Yersinia, human tissue libraries, and mouse macrophages.
- These publicly available data cover diverse data types such as mass spectrometry, yeast two-hybrid (Y2H), gene expression profiles, X-ray and NMR determined protein structures and protein expression clones.
- The growing database covers over 23 000 unique genes/proteins from different experiments and organisms.
- All of the genes/proteins are annotated and integrated across experiments using UniProt Knowledgebase (UniProtKB) accession numbers.
- The web-interface for the database enables searching, querying and downloading at the level of experiment, group and individual gene(s)/protein(s) via UniProtKB accession numbers or protein function keywords.
Keywords:
- Bacterial Proteins
- Bioterrorism
- biodefense
- Gene Expression Profiling
- Host-Pathogen Interactions
- Humans
- Infection
- Mice
- Proteomics
- Protozoan Proteins
- Viral Proteins
- Bacillus
- Brucella
- Cryptosporidium
- Salmonella
- SARS
- Toxoplasma
- Vibrio
- Yersinia
Literature & Tutorials:
This record last updated: 04-15-2008