NetworKIN -- a resource for exploring cellular phosphorylation networks
What you can do:
Highlights:
- NetworKIN integrates consensus substrate motifs with context modelling for improved prediction of cellular kinase-substrate relations.
- Based on the latest human phosphoproteome from the Phospho.ELM and PhosphoSite databases, the resource offers insight into phosphorylation-modulated interaction networks.
- NetworKIN can be used for both global and targeted molecular studies.
- Via the web interface users can query the database of precomputed kinase-substrate relations or obtain predictions on novel phosphoproteins.
- The database currently contains a predicted phosphorylation network with 20,224 site-specific interactions involving 3978 phosphoproteins and 73 human kinases from 20 families.
Keywords:
- Amino Acid Sequence
- Consensus Sequence
- Phosphoproteins
- Phosphorylation
- Protein Kinases metabolism
- kinase
Literature & Tutorials:
This record last updated: 04-17-2008