miRGator -- an integrated system for functional annotation of microRNAs

What you can do:
Database and navigator tool for functional interpretation of miRNAs.
Highlights:
  • miRGator integrates target prediction, functional analysis, gene expression data and genome annotation.
  • MiRNA function is inferred from the list of target genes predicted by miRanda, PicTar and TargetScanS programs.
  • Statistical enrichment test of target genes in each term is performed for gene ontology, pathway and disease annotations.
  • For the expression analysis, miRGator integrates public expression data of miRNA with those of mRNA and protein.
  • Expression correlation between miRNA and target mRNA/proteins is evaluated and their expression patterns can be readily compared.
  • Our web implementation supports diverse query types including miRNA name, gene symbol, gene ontology, pathway and disease terms.
  • Interfaces for exploring common targets or regulatory miRNAs and for profiling compendium expression data have been developed as well.
Keywords:
  • Gene Expression Profiling
  • Gene Silencing
  • MicroRNAs
  • miRNA
  • mRNA
  • functional analysis
  • expression profiling
  • human
  • mouse
This record last updated: 05-01-2008
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