piRNABank -- a web resource on classified and clustered Piwi-interacting RNAs
What you can do:
Provides information on piRNAs in Human, Mouse, Rat, and Drosophila.
Highlights:
- Piwi-interacting RNAs (piRNAs) are expressed in mammalian germline cells and have been identified as key players in germline development.
- These molecules, typically of length 25-33 nt, associate with Piwi proteins of the Argonaute family to form the Piwi-interacting RNA complex.
- These small regulatory RNAs have been implicated in spermatogenesis, repression of retrotransposon transposition in germline cells, epigenetic regulation and positive regulation of translation and mRNA stability.
- piRNABank is a highly user-friendly resource which stores empirically known sequences and other related information on piRNAs reported in human, mouse and rat.
- The database supports organism and chromosome-wise comprehensive search features including accession numbers, localization on chromosomes, gene name or symbol, sequence homology-based search, clusters and corresponding genes and repeat elements.
- It also displays each piRNA or piRNA cluster on a graphical genome-wide map.
Keywords:
- RNA Interference
- Small Interfering RNA
- piRNA
- human
- mouse
- rat
- Drosophila
- Piwi-interacting RNA
Literature & Tutorials:
This record last updated: 05-01-2008