RNABindR -- software for prediction of RNA binding residues in proteins
What you can do:
Web-based server for analyzing and predicting RNA binding sites in proteins.
Highlights:
- RNABindR is a web-based server that identifies and displays RNA-binding residues in known protein-RNA complexes and predicts RNA-binding residues in proteins of unknown structure.
- RNABindR uses a distance cutoff to identify which amino acids contact RNA in solved complex structures (from the Protein Data Bank) and provides a labeled amino acid sequence and a Jmol graphical viewer in which RNA-binding residues are displayed in the context of the three-dimensional structure.
- Alternatively, RNABindR can use a Naive Bayes classifier trained on a non-redundant set of protein-RNA complexes from the PDB to predict which amino acids in a protein sequence of unknown structure are most likely to bind RNA.
- RNABindR automatically displays 'high specificity' and 'high sensitivity' predictions of RNA-binding residues.
Keywords:
- Bayes Theorem
- Binding Sites
- Protein Conformation
- RNA binding residues
- protein-RNA complexes
- protein-RNA complex
Literature & Tutorials:
This record last updated: 06-02-2008