eF-seek -- prediction of the functional sites of proteins by searching for similar electrostatic potential and molecular surface shape

What you can do:
Predict the functional sites of proteins.
  • We have developed a method to predict ligand-binding sites in a new protein structure by searching for similar binding sites in the Protein Data Bank (PDB).
  • The similarities are measured according to the shapes of the molecular surfaces and their electrostatic potentials.
  • A new web server, eF-seek, provides an interface to our search method.
  • It simply requires a coordinate file in the PDB format, and generates a prediction result as a virtual complex structure, with the putative ligands in a PDB format file as the output.
  • In addition, the predicted interacting interface is displayed to facilitate the examination of the virtual complex structure on our own applet viewer with the web browser.
  • Binding Sites
  • Electrostatics
  • Ligands
  • Protein Conformation
  • protein function
  • functional sites
  • ligand-binding sites
This record last updated: 06-04-2008
Report a missing or misdirected URL.

The Health Sciences Library System supports the Health Sciences at the University of Pittsburgh.

© 1996 - 2023 Health Sciences Library System, University of Pittsburgh. All rights reserved.