RNAbor -- a web server for RNA structural neighbors

What you can do:
Compute structural neighbors of an RNA secondary structure.
Highlights:
  • RNAbor provides a new tool for researchers in the biological and related sciences to explore important aspects of RNA secondary structure and folding pathways.
  • RNAbor computes statistics concerning delta-neighbors of a given input RNA sequence and structure (the structure can, for example, be the minimum free energy (MFE) structure).
  • A delta-neighbor is a structure that differs from the input structure by exactly delta base pairs, that is, it can be obtained from the input structure by adding and/or removing exactly delta base pairs.
  • For each distance delta RNAbor computes the density of delta-neighbors, the number of delta-neighbors, and the MFE structure, or MFE (delta) structure, among all delta-neighbors.
  • RNAbor can be used to study possible folding pathways, to determine alternate low-energy structures, to predict potential nucleation sites and to explore structural neighbors of an intermediate, biologically active structure.
Keywords:
  • Cluster Analysis
  • Conserved Sequence
  • Molecular Sequence Data
  • Nucleic Acid Conformation
  • RNA
  • Untranslated RNA
  • Regulatory Sequences
  • Sequence Alignment
  • Sequence Analysis
  • Sequence Homology
  • RNA structure
  • RNA secondary structure
  • RNA folding pathways
Literature & Tutorials:
This record last updated: 06-04-2008
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