SLiMDisc -- Short, Linear Motif Discovery
What you can do:
Find shared motifs in proteins with a common attribute.
Highlights:
- The SLiMDisc web server corrects for common ancestry in describing shared motifs, concentrating on the convergently evolved motifs.
- The server returns a listing of the most interesting motifs found within unmasked regions, ranked according to an information content-based scoring scheme.
- It allows interactive input masking, according to various criteria.
- Scoring allows for evolutionary relationships in the data sets through treatment of BLAST local alignments.
- Alongside this ranked list, visualizations of the results improve understanding of the context of suggested motifs, helping to identify true motifs of interest.
- These visualizations include alignments of motif occurrences, alignments of motifs and their homologues and a visual schematic of the top-ranked motifs.
- Additional options for filtering and/or re-ranking motifs further permit the user to focus on motifs with desired attributes.
- Returned motifs can also be compared with known SLiMs from the literature.
Keywords:
- Amino Acid Motifs
- Amino Acid Sequence
- Molecular Sequence Data
- Sequence Analysis
- Sequence Homology
- motif
Literature & Tutorials:
This record last updated: 06-05-2008