MolAxis -- a server for identification of channels in macromolecules
What you can do:
Accurate identification of channels in macromolecules.
Highlights:
- MolAxis implements state-of-the-art, accurate computational-geometry techniques that reduce the dimensions of the channel finding problem, rendering the algorithm extremely efficient.
- Given a protein or nucleic acid structure in the PDB format, the server outputs all possible channels that connect buried cavities to the outside of the protein or points to the main channel in TM proteins.
- For each channel, the gating residues and the narrowest radius termed 'bottleneck' are also given along with a full list of the lining residues and the channel surface in a 3D graphical representation.
- The users can manipulate advanced parameters and direct the channel search according to their needs.
Keywords:
- protein channel
- macromolecules
- macromolecule channel
- transmembrane channel
- tm channel
Literature & Tutorials:
This record last updated: 07-23-2008