MAPPIS -- Multiple Alignment of Protein-Protein InterfaceS

URL:
http://bioinfo3d.cs.tau.ac.il/MAPPIS
What you can do:
Recognize spatially conserved chemical interactions shared by a set of PPIs.
Highlights:
  • MAPPIS aims to analyze protein-protein interactions.
  • It performs multiple alignment of protein-protein interfaces (PPIs), which are regions of interaction between two protein molecules.
  • MAPPIS recognizes the spatially conserved physico-chemical interactions, which often involve energetically important hot-spot residues that are crucial for protein-protein associations.
  • The input to the MAPPIS server is a set of protein-protein complexes.
  • The output is a detailed list of the shared interaction properties of the interfaces.
Keywords:
  • protein multiple alignment
  • protein-protein interactions
  • protein-protein interfaces
  • PPIs
  • protein interaction
  • protein-protein associations
  • protein-protein complexes
Literature & Tutorials:
PubMed Link: MultiBind and MAPPIS: webservers for multiple alignment of protein 3D-binding sites and their interactions
This record last updated: 07-24-2008
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