Predikin -- predict substrates of protein kinases
What you can do:
Prediction of protein kinase peptide specificity using structural information.
Highlights:
- The Predikin system is built from three components: a database of protein kinase substrates that links phosphorylation sites with specific protein kinase sequences; a perl module to analyse query protein kinases and a web interface through which users can submit protein kinases for analysis.
- The Predikin perl module provides methods to (i) locate protein kinase catalytic domains in a sequence, (ii) classify them by type or family, (iii) identify substrate-determining residues, (iv) generate weighted scoring matrices using three different methods, (v) extract putative phosphorylation sites in query substrate sequences and (vi) score phosphorylation sites for a given kinase, using optional filters.
- The web interface provides user-friendly access to each of these functions and allows users to obtain rapidly a set of predictions that they can export for further analysis.
Keywords:
- protein kinase peptide
- kinase
- protein kinase sequence
- protein kinase
Literature & Tutorials:
This record last updated: 07-25-2008