KEGG Atlas -- mapping for global analysis of metabolic pathways
What you can do:
A new graphical interface to the KEGG suite of databases, especially to the systems information in the PATHWAY and BRITE databases.
Highlights:
- KEGG Atlas is a new graphical interface to the KEGG suite of databases, especially to the systems information in the PATHWAY and BRITE databases.
- It currently consists of a single global map and an associated viewer for metabolism, covering about 120 KEGG metabolic pathway maps and about 10 BRITE hierarchies.
- The viewer allows the user to navigate and zoom the global map under the Ajax technology.
- The mapping of high-throughput experimental data onto the global map is the main use of KEGG Atlas.
- In the global metabolism map, the node (circle) is a chemical compound and the edge (line) is a set of reactions linked to a set of KEGG Orthology (KO) entries for enzyme genes.
- Once gene identifiers in different organisms are converted to the K number identifiers in the KO system, corresponding line segments can be highlighted in the global map, allowing the user to view genome sequence data as organism-specific pathways, gene expression data as up- or down-regulated pathways, etc.
- Once chemical compounds are converted to the C number identifiers in KEGG, metabolomics data can also be displayed in the global map.
Keywords:
- KEGG
- metabolic pathway
- KEGG orthology
- metabolomics
- metabolism
Literature & Tutorials:
This record last updated: 07-29-2008