MassTRIX -- Mass TRanslator into Pathways

What you can do:
Annotate metabolites in high precision mass spectrometry data.
  • Recent technical advances in mass spectrometry (MS) have brought the field of metabolomics to a point where large numbers of metabolites from numerous prokaryotic and eukaryotic organisms can now be easily and precisely detected.
  • The challenge today lies in the correct annotation of these metabolites on the basis of their accurate measured masses.
  • Assignment of bulk chemical formula is generally possible, but without consideration of the biological and genomic context, concrete metabolite annotations remain difficult and uncertain.
  • MassTRIX responds to this challenge by providing a hypothesis-driven approach to high precision MS data annotation.
  • It presents the identified chemical compounds in their genomic context as differentially colored objects on KEGG pathway maps.
  • Information on gene transcription or differences in the gene complement (e.g. samples from different bacterial strains) can be easily added.
  • The user can thus interpret the metabolic state of the organism in the context of its potential and, in the case of submitted transcriptomics data, real enzymatic capacities.
  • mass spectrometry
  • metabolites
  • metabolomics
  • metabolic
Literature & Tutorials:
This record last updated: 07-29-2008
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