A web-server that searches a protein sequence for CBS composed of user-specified amino acid types.
Highlights:
ProBias utilizes the discrete scan statistics to estimate statistical significance of CBS and is able to detect even subtle local deviations from the random independence model.
The web-server also analyzes the global compositional bias of the input sequence.
In the case of novel proteins that lack functional annotation, statistically significant CBS reported by ProBias can be used to guide the search for potential functionally important sites or domains.
