BiasViz -- visualization of amino acid biased regions in protein alignments

What you can do:
A tool to graphically study local amino acid composition in protein sequences of a multiple sequence alignment.
Highlights:
  • About a third of all protein sequences have at least one composition biased region (CBR).
  • Such regions might act as linkers between protein domains but often confer specific binding to various molecules; therefore, their characterization in terms of their boundaries and over-represented residues is important.
  • Analysis of CBRs in a particular sequence can be time consuming if several types of biases have to be explored and their position visualized.
  • Assessment of the significance of the detected CBRs can be approached by comparison to homologous protein sequences.
Keywords:
  • amino acid bias
  • protein sequence alignment
  • composition biased region
This record last updated: 08-07-2008
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