RFRCDB-siRNA -- Design of siRNA with Random Forest Regression Model Coupled with Database Searching

URL:
http://www.bioinf.seu.edu.cn/siRNA/index.htm
What you can do:
Predict siRNA efficacy.
Highlights:
  • RFRCDB-siRNA consists of two modules: a siRNA-centric database and a RFR prediction system.
  • RFRCDB-siRNA works as follows: (1) Instead of directly predicting the gene silencing activity of siRNAs, the service takes these siRNAs as queries to search against the siRNA-centric database. The matched sequences with the exceeding the user defined functionality value threshold are kept. (2) The mismatched sequences are then processed into the RFR prediction system for further analysis.
Keywords:
  • RNA Interference
  • Small Interfering RNA
  • Regression Analysis
  • siRNA
  • gene silencing
Literature & Tutorials:
PubMed Link: RFRCDB-siRNA: improved design of siRNAs by random forest regression model coupled with database searching
This record last updated: 08-07-2008
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