DBD-Hunter -- DNA-binding Domain Hunter

What you can do:
A knowledge-based method for the prediction of DNA-protein interactions.
Highlights:
  • DBD-Hunter identifys DNA-binding proteins and associated binding sites.
  • The method combines structural comparison and the evaluation of a statistical potential, which we derive to describe interactions between DNA base pairs and protein residues.
  • We demonstrate that DBD-Hunter is an accurate method for predicting DNA-binding function of proteins, and that DNA-binding protein residues can be reliably inferred from the corresponding templates if identified.
Keywords:
  • Binding Sites
  • DNA-Binding Proteins
  • Protein Conformation
  • Protein Structural Homology
  • DNA-protein interactions
This record last updated: 04-17-2014
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