Exalign -- a new method for comparative analysis of exon-intron gene structures
What you can do:
An algorithm designed to retrieve, compare and search for the exon-intron structure of existing gene annotations.
Highlights:
- The evolution of genes is usually studied and reconstructed at the sequence level, that is, by comparing and aligning their genomic, transcript or protein sequences.
- However, including the exon-intron structure of genes in the analysis can provide further and useful information, for example to draw reliable phylogenetic relationships left unsolved by traditional sequence-based evolutionary studies, or to shed further light on patterns of intron gain and loss.
Keywords:
- exon-intron
- gene structure
- phylogenetic relationships
Literature & Tutorials:
This record last updated: 04-18-2014