ProfDistS -- (Profile-) Distance based phylogeny on sequence - structure alignments
What you can do:
A tool for the construction of large phylogenetic trees based on profile distances.
Highlights:
- The Profile Neighbor Joining (PNJ) algorithm as implemented in the software ProfDist is computationally efficient in reconstructing very large trees.
- Besides the huge amount of sequence data the structure is important in RNA alignment analysis and phylogenetic reconstruction.
- For this ProfDistS provides a phylogenetic workflow that uses individual RNA secondary structures in reconstructing phylogenies based on sequence-structure alignments - using Profile Neighbor Joining (PNJ) with manual or iterative and automatic profile definition.
- ProfDistS can deal also with protein sequences.
Keywords:
- phylogenetic tree
- RNA secondary structure
- sequence-structure alignment
- profile neighbor joining
- RNA alignment
Literature & Tutorials:
This record last updated: 09-03-2008