TOPDOM -- Conservatively Located Domains and Motifs in Transmembrane Proteins
What you can do:
Database of domains and motifs with conservative location in transmembrane proteins.
Highlights:
- The TOPDOM database is a collection of domains and sequence motifs located consistently on the same side of the membrane in alpha-helical transmembrane proteins.
- The database was created by scanning well-annotated transmembrane protein sequences in the UniProt database by specific domain or motif detecting algorithms.
- The identified domains or motifs were added to the database if they were uniformly annotated on the same side of the membrane of the various proteins in the UniProt database.
- The information about the location of the collected domains and motifs can be incorporated into constrained topology prediction algorithms, like HMMTOP, increasing the prediction accuracy.
Keywords:
- Protein Structure
- protein sequence analysis
- Membrane Proteins
- Amino Acid Motifs
- protein motif
- transmembrane protein
- protein domain
Literature & Tutorials:
This record last updated: 09-03-2008