OKCAM -- an ontology-based knowledgebase for cell adhesion molecules

What you can do:
Locate information on cell adhesion molecules (CAMs).
Highlights:
  • We now report compilation of 496 human CAM genes in six gene families based on manual curation of protein domain structures, Gene Ontology annotations, and 1487 NCBI Entrez annotations.
  • We map these genes onto a cell adhesion molecule ontology that contains 850 terms, up to seven levels of depth and provides a hierarchical description of these molecules and their functions.
  • We identify global CAM properties that include: (i) functional enrichment, (ii) over-represented regulation modes and expression patterns and (iii) relationships to human Mendelian and complex diseases, and discuss the strengths and limitations of these data.
Keywords:
  • CAM
  • cell adhesion molecule
This record last updated: 09-15-2008

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