MANTIS -- a phylogenetic framework for multi-species genome comparisons
What you can do:
The missing link between multi-species full genome comparisons and functional analysis.
Highlights:
- MANTIS is a relational database for the analysis of (i) gains and losses of genes on specific branches of the metazoan phylogeny, (ii) reconstructed genome content of ancestral species and (iii) over- or under-representation of functions/processes and tissue specificity of gained, duplicated and lost genes.
- MANTIS estimates the most likely positions of gene losses on the true phylogeny using a maximum-likelihood function.
- A user-friendly interface and an extensive query system allow to investigate questions pertaining to gene identity, phylogenetic mapping and function/expression parameters.
Keywords:
- comparative genomics
- genome comparison
- phylogeny
- phylogenetic mapping
Literature & Tutorials:
This record last updated: 12-9-2008