SysPimp -- Systematic Platform for Identifying Mutated Proteins
What you can do:
Identify human disease-related mutated proteins within mass spectrometry results.
Highlights:
- SysPIMP comprises of three layers: (i) a standardized data warehouse, (ii) a pipeline layer for maintaining human disease databases and X!Tandem and BLAST and (iii) a web-based interface.
- From OMIM AV part, PMD and SwissProt databases, 35,497 non-redundant human disease-related mutated sequences were collected with disease information described by OMIM terms.
- With the interfaces to browse sequences archived in SysPIMP, X!Tandem, an open source database-search engine used to identify proteins within MS data, was integrated into SysPIMP to help support the detection of potential human disease-related mutants in MS results.
- In addition, together with non-redundant disease-related mutated sequences, original non-mutated sequences are also provided in SysPIMP for comparative research.
Keywords:
- mass spectrometry
- protein mutations
- human disease
- homo sapien
Literature & Tutorials:
This record last updated: 03-15-2010