metaTIGER -- a metabolic gene evolution resource
What you can do:
Find metabolic networks and phylogenomic information on a taxonomically diverse range of eukaryotes.
Highlights:
- metaTIGER uses genomic information from 121 eukaryotes and 404 prokaryotes and sensitive sequence search techniques to predict the presence of metabolic enzymes.
- These enzyme sequences were used to create a comprehensive database of 2257 maximum-likelihood phylogenetic trees, some containing over 500 organisms.
- The trees can be viewed using iTOL, an advanced interactive tree viewer, enabling straightforward interpretation of large trees.
- Complex high-throughput tree analysis is also available through user-defined queries, allowing the rapid identification of trees of interest, e.g. containing putative HGT events.
- metaTIGER also provides novel and easy-to-use facilities for viewing and comparing the metabolic networks in different organisms via highlighted pathway images and tables.
- metaTIGER is demonstrated through evolutionary analysis of Plasmodium, including identification of genes horizontally transferred from chlamydia.
Keywords:
- metabolism
- biosynthesis
- biodegradation
- unicellular eukaryotes
- bacteria
- fungi
- metabolic pathways
Literature & Tutorials:
PubMed Link: metaTIGER: a metabolic evolution resource
This record last updated: 02-11-2009