CAZy -- Carbohydrate-Active enZymes database

What you can do:
Find information about the families of structurally-related catalytic and carbohydrate-binding modules (or functional domains) of enzymes that degrade, modify, or create glycosidic bonds.
  • CAZy is a knowledge-based resource specialized in the enzymes that build and breakdown complex carbohydrates and glycoconjugates.
  • The database describes the present knowledge on 113 glycoside hydrolase, 91 glycosyltransferase, 19 polysaccharide lyase, 15 carbohydrate esterase and 52 carbohydrate-binding module families.
  • These families are created based on experimentally characterized proteins and are populated by sequences from public databases with significant similarity.
  • Protein biochemical information is continuously curated based on the available literature and structural information.
  • Over 6400 proteins have assigned EC numbers and 700 proteins have a PDB structure.
  • The classification (i) reflects the structural features of these enzymes better than their sole substrate specificity, (ii) helps to reveal the evolutionary relationships between these enzymes and (iii) provides a convenient framework to understand mechanistic properties.
  • glycogenomics
  • enzyme
  • carbohydrate
  • glycoconjugates
This record last updated: 03-06-2009
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