SDR -- Specificity Determining Residues Database
What you can do:
Predict specificity-determining residues in protein families.
Highlights:
- The specificity-determining residue database (SDR database) presents residue positions where mutations are predicted to have changed protein function in large protein families.
- Because the database pre-calculates predictions on existing protein sequence alignments, users can quickly find the predictions by selecting the appropriate protein family or searching by protein sequence.
- Predictions can be used to guide mutagenesis or to gain a better understanding of specificity changes in a protein family.
- SDR uses the PFAM database of protein domains for sequence alignments and domain definitions as well as the GPCR database for G-protein coupled receptors.
Keywords:
- mutagenesis
- protein family
- functional residue
- protein sequence alignment
Literature & Tutorials:
This record last updated: 04-21-2014