PTM-Switchboard -- Post-Translational Modifications of Transcription Factors Database

URL:
http://cagr.pcbi.upenn.edu/PTMswitchboard
What you can do:
Find information about 'molecular switchboards'.
Highlights:
  • PTM-Switchboard is a database of known instances of TF-PTMs affecting transcriptional regulation in the model system Saccharomyces cerevisia.
  • The database stores triplets of genes such that the ability of one gene (TF) to regulate a target gene is dependent on one or more PTMs catalyzed by a third gene (modifying enzyme).
  • The database currently includes a large sample of experimentally characterized instances curated from the literature.
  • In addition to providing a framework for searching and analyzing the data, the database will serve to benchmark computational methods.
  • In the future, the database will be expanded to mammalian organisms, and will also include triplets predicted from computational approaches.
Keywords:
  • post-translational modification
  • transcription factor
  • molecular switchboard
  • transcription factor
Literature & Tutorials:
PubMed Link: PTM-Switchboard--a database of posttranslational modifications of transcription factors, the mediating enzymes and target genes
This record last updated: 04-01-2009
Report a missing or misdirected URL.

The Health Sciences Library System supports the Health Sciences at the University of Pittsburgh.

© 1996 - 2023 Health Sciences Library System, University of Pittsburgh. All rights reserved.