Berkeley PHOG -- Phylofacts Orthology Group prediction
What you can do:
Detect orthologs for functional genome analysis.
Highlights:
- PHOG is a web server that employs a novel algorithm to identify orthologs based on phylogenetic analysis.
- Results on a benchmark dataset from the TreeFam-A manually curated orthology database show that PHOG provides a combination of high recall and precision, and allows users to target different taxonomic distances and precision levels through the use of tree-distance thresholds.
- PHOG is based on pre-computed trees in the PhyloFacts resource, and contains over 366 K orthology groups with a minimum of three species.
- Predicted orthologs are linked to GO annotations, pathway information and biological literature.
Keywords:
- phylogeny
- ortholog detection
- super-ortholog
- protein family phylogenies
- PhyloFact
- protein-protein interaction
- phylogenetic tree construction
Literature & Tutorials:
This record last updated: 09-10-2009