TargetMiner -- microRNA target prediction web server

URL:

http://www.isical.ac.in/~bioinfo_miu/targetminer20.htm

What you can do:

Find information about microRNA target mRNA.

Highlights:

TargetMiner is a support vector machine (SVM)-based classifier that systematically identifies non-target mRNAs to address the problem that current machine learning approaches are compelled to rely on artificially generated negative examples for training.
300 tissue-specific negative examples were used using a novel approach that involves expression profiling of both miRNAs and mRNAs, miRNA-mRNA structural interactions and seed-site conservation.
The newly generated negative examples are validated with pSILAC dataset, which elucidate the fact that the identified non-targets are indeed non-targets.
These high-throughput tissue-specific negative examples and a set of experimentally verified positive examples are then used to build TargetMiner.

Keywords:

Literature & Tutorials:

PubMed Link: GAzer: gene set analyzer

This record last updated: 10-13-2009